I've been pondering your message for a while, sorry that I didn't get
back sooner. I have said that I feel 10 times more food chemical
sensitive during certain parts of my cycle. That is: during days 25-28
(pre period) and days 1-8 (during and just after period).

There is a graph on estrogen levels per day, deep in this article that I
found online:
http://itech.fgcu.edu/&/issues/vol1/issue2/hormone.htm
labled "estrogen vs time". (The article is trying to find mathematical
equations that match with the dynamic fluctuations of the female hormone
cycle. The pink line is the one I think you want to look at. I hope
I'm not misunderstanding this chart, I haven't read the whole article,
but it seemed to be showing what I wanted to know.)

The days in which I seem to be most sensitive, most apt to end up with
an amine headache or full out migraine, have difficulty sleeping, are
when estrogen levels are below 100 pg/ml in serum.

(The other chart which shows progesterone levels doesn't seem to
correspond with my sensitive days at all.)

I always assumed that I'm a person who is low in estrogen - skin and
bones and muscle, no bust, shaped like a 12 year old boy. (My cycle is
regular, (though painful), no fertility probs.)

I guess what I'm saying is exactly opposite your point - that my food
sensitivities seem to be inversely proportional to the amount of
estrogens in my body. But, I *am* saying that it sure seems like
estrogen is part of the equation...for me.

There are some discussion on plant poisons and rotten stuff about
estrogens, serotonin, MAOs, gene polymmorphisms...also I found the
following quotes online.

I found this here: (http://www.selfgrowth.com/articles/Dowling1.html):
"Why does this happen? Because serotonin needs estrogen for its
metabolization in the brain. The two hormones are a dynamic duo,
functioning in tandem. As estrogen levels drop, so does serotonin. When
estrogen rises (as it does, for example, once menstruation begins)
serotonin levels come right back up, and calm is restored."

"Like pharmaceutical monoamine oxidase (MAO) inhibitors, estrogen
reduces MAO activity, resulting in higher levels of both catecholamines
and serotonin in the brain.[40] Estrogen also increases opioid and
endorphin production by the hypothalamus.[41]"


Renee



surely_5 wrote:
> Hello! I've been reading many of the threads on this forum, trying to
understand the subject
> better. About 3.5 years ago, I started avoiding foods high in phytoestrogen,
which
> significantly decreased my endometriosis symptoms. However, now that I know
about
> Failsafe, I know that some of the high estrogen foods are also foods to be
avoided on the
> Failsafe diet. I was also eating certain foods high in amines and and
salicylates, so now I'm
> wondering if it's all just an issue of threshold (for me) or if avoiding
phytoestrogens takes
> the burden off the detox process, therefore allowing me to process the high
amine and
> salicylate food I was eating. I've found a small amount of information that
says there's a
> similar or same pathway that's used for both estrogen (not sure which estrogen
they meant)
> and salicylates (perhaps also amines?). Any thoughts?
>
> Thanks! Cheryl
>
>
>
>
>
> ------------------------------------
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