I had a CT scan on 9/21/04 and received, what I consider, a
good initial response after being on the drug for eight weeks. I
have an aggressive sarcoma called DSRCT.

Three of my main tumor areas showed stability. One tumor mass
grew about twenty percent. (When added up together, all four tumor
masses grew about five percent.)

I'll have another CT scan around December 15th. After about
four weeks, I noticed that I had a little less energy than before I
started the drug. I've noticed no other symptoms.

Several other AMG 706 patients that I've met said that they
have experienced some fatigue, slightly higher blood pressure and
some mild diarrhea.

One of my fellow DSRCT patients who started the trial a week
before I did showed overall stabilty after their eighth week scan.

Patrick