Medications used to treat depression. During depressive episodes, people
with bipolar disorder may need additional treatment with an
antidepressant medication. Because of the risk of triggering mania,
doctors often prescribe an antidepressant only after the individual is
already receiving a therapeutic dose of lithium or an anticonvulsant
mood stabilizer.
Research suggests that mood stabilizers can protect against
antidepressant-induced switches into mania. Antidepressant medications
relieve depression, elevate mood, and activate behavior, but it often
takes three to four weeks to respond.
Sometimes a variety of different antidepressants and doses will be tried
before finding the medication that works best for a particular
individual.
* There are several different types of antidepressants used to
treat depression including tricyclic antidepressants (TCAs), monoamine
oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors
(SSRIs), or newer antidepressants that function in different ways.
Recent data suggests that the anticonvulsant lamotrigine (Lamictal) may
possess antidepressant effects in bipolar disorder.
Once again, it is important to emphasize that treatment of depression in
bipolar disorder without a mood stabilizing medication may result in
"cycling" into a manic episode
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